Marginal zone B-cell lymphoma is a type of non-Hodgkin lymphoma that affects a type of white blood cell called B-lymphocytes. This type of lymphoma typically arises in the marginal zone of the lymphoid tissue and can manifest in different parts of the body, including the stomach, salivary glands, thyroid, and spleen. Like many types of cancer, early detection and treatment are crucial for improving outcomes, making it important to be aware of the symptoms of marginal zone B-cell lymphoma.
In this article, we will explore the common symptoms associated with marginal zone B-cell lymphoma, as well as the importance of seeking medical attention if you experience any of these symptoms.
Unexplained weight loss
Unexplained weight loss can be a common symptom of marginal zone B-cell lymphoma. It is defined as a weight loss of more than 5% of normal body weight over a period of 6-12 months without any changes in diet or exercise. This can be a result of the lymphoma affecting the body’s metabolism and energy expenditure.
If you have been experiencing unexplained weight loss, especially in conjunction with other symptoms such as night sweats and fatigue, it is important to consult a healthcare professional for further evaluation.
Enlarged lymph nodes
Another common symptom of marginal zone B-cell lymphoma is the presence of enlarged lymph nodes. These can often be felt as lumps under the skin in areas such as the neck, armpits, or groin. In some cases, the lymph nodes may also be painless, making them easy to miss.
If you notice any unusual lumps or swelling in your lymph nodes, it is important to have them evaluated by a healthcare provider, as they could be a sign of an underlying condition such as lymphoma.
Abdominal pain or discomfort
Some individuals with marginal zone B-cell lymphoma may experience abdominal pain or discomfort, especially if the lymphoma is affecting the stomach or other organs in the abdominal cavity. This pain can range from mild to severe and may be accompanied by other symptoms such as bloating or changes in bowel habits.
If you have been experiencing persistent abdominal pain or discomfort, it is important to seek medical attention to rule out any potential underlying causes, including lymphoma.
Fevers and night sweats
Fevers and night sweats are common symptoms of many types of lymphoma, including marginal zone B-cell lymphoma. These symptoms may occur intermittently and can be accompanied by chills and a general feeling of being unwell. Night sweats are often described as severe hot flashes that soak through clothing and bedding.
If you have been experiencing unexplained fevers and night sweats, especially if they are severe or persistent, it is important to consult a healthcare professional for further evaluation.
Fatigue and weakness
Fatigue and weakness are common symptoms that can occur as a result of marginal zone B-cell lymphoma. These symptoms can significantly impact a person’s quality of life and ability to carry out daily activities. The underlying cause of fatigue in lymphoma patients is not fully understood, but it is believed to be related to the body’s immune response and the lymphoma’s effect on the body’s energy production.
If you have been experiencing persistent fatigue and weakness, it is important to discuss these symptoms with a healthcare provider to determine the underlying cause and receive appropriate care.
Unexplained itching
Unexplained itching, also known as pruritus, can be a symptom of marginal zone B-cell lymphoma. This itching may be generalized or localized to specific areas of the body and can be quite bothersome for some individuals. It is thought to be related to the release of certain chemicals by the lymphoma cells.
If you have been experiencing unexplained itching, especially in conjunction with other symptoms such as night sweats or enlarged lymph nodes, it is important to seek medical attention for further evaluation.
Weakness and numbness in extremities
In some cases, marginal zone B-cell lymphoma may cause weakness and numbness in the extremities, such as the arms and legs. This can occur if the lymphoma is affecting the nerves or spinal cord. If you experience weakness or numbness in your extremities, it is important to seek medical attention promptly to determine the underlying cause.
Shortness of breath
Shortness of breath can be a symptom of marginal zone B-cell lymphoma if the lymphoma is affecting the chest or the lungs. This can occur due to the accumulation of fluid or lymphoma cells in the chest cavity, causing compression of the lungs and making it difficult to breathe. If you have been experiencing persistent shortness of breath, it is important to seek prompt medical attention.
Changes in bowel habits
In some cases, individuals with marginal zone B-cell lymphoma may experience changes in bowel habits, such as diarrhea, constipation, or changes in stool consistency. These changes can be a result of the lymphoma affecting the intestines or other organs in the abdominal cavity. If you have been experiencing changes in your bowel habits, it is important to discuss these symptoms with a healthcare provider for further evaluation.
Swelling in the abdomen
Swelling in the abdomen, also known as ascites, can occur in some individuals with marginal zone B-cell lymphoma if the lymphoma is affecting the liver or other organs in the abdominal cavity. Ascites can cause abdominal distention, discomfort, and difficulty eating or breathing. If you have been experiencing abdominal swelling, it is important to seek medical attention for further evaluation.
